HC Q study #81
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8/14
Inconc.
Late treatment study
Abd-Elsalam et al., American Journal of Tropical Medicine and Hygiene, 10.4269/ajtmh.20-0873 (Peer Reviewed)
Hydroxych loroquine in the Treatment of COVID-19: A Multicenter Randomized Controlled Study
Small RCT in Egypt with 97/97 HC Q/control patients, showing 58% more recovery @28days for HC Q (53.6% HC Q, 34% control), p=0.009 (0.06 in the paper refers to the 5 combined recovery/death/ICU values).
No significant difference in ventilation and mortality (<=6 examples in each case). Authors note the "sample size was not adequately powered for [the] survival endpoint".
Other studies have also shown treated patient cases resolved faster. Continuing analysis past 28 days would be useful. Group characteristics are given, with for example 36% vs. 26% smokers, but they do not identify which group is which. Group 1 and 2 have 97 patients but the total given is 175.
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