et al., American Journal of Tropical Medicine and Hygiene, 10.4269/ajtmh.20-0873 (Peer Reviewed)
Small RCT in Egypt with 97/97 HC
Q/control patients, showing 58% more recovery @28days for HC
Q (53.6% HC
Q, 34% control), p
=0.009 (0.06 in the paper refers to the 5 combined recovery/death/ICU values).
No significant difference in ventilation and mortality (<=6 examples in each case). Authors note the "sample size was not adequately powered for [the] survival endpoint".
Other studies have also shown treated patient cases resolved faster. Continuing analysis past 28 days would be useful. Group characteristics are given, with for example 36% vs. 26% smokers, but they do not identify which group is which. Group 1 and 2 have 97 patients but the total given is 175.
death, ↑20.0%, p=1.00
no recovery, ↓30.0%, p=0.009, risk of no recovery at day 28