loroquine and Hydroxych loroquine, 2014, 35-63, doi:10.1007/978-1-4939-0597-3_2 (Peer Reviewed) (not included in the study count)
, D., Pharmacology of Ch
Pharmacology of Ch loroquine and Hydroxych loroquine
Review of the pharmacology of C
Q and HC
Q. Some notable points:
Q and C
Q are equipotent but C
Q is more toxic, the therapeutic ratio is higher for HC
- Concentrations in different tissues can vary >10x, in particular the concentration in the lung is much higher in animal experiments.
- Tissue uptake as a function of dosage is nonlinear.
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