Situación de la infección por SARS-CoV-2 en pacientes en tratamiento renal sustitutivo. Informe del Registro COVID-19 de la Sociedad Española de Nefrología (SEN)
J Emilio Sánchez-Álvarez, Miguel Pérez Fontán, Carlos Jiménez Martín, Miquel Blasco Pelícano, Carlos Jesús Cabezas Reina, Ángel M Sevillano Prieto, Edoardo Melilli, Marta Crespo Barrios, Manuel Macía Heras, María Dolores Del Pino Y Pino
Nefrología, doi:10.1016/j.nefro.2020.04.002
Introduction: The recent appearance of the SARS-CoV-2 coronavirus pandemic has had a significant impact on the general population. Patients on renal replacement therapy (RRT) have not been unaware of this situation and due to their characteristics they are especially vulnerable. We present the results of the analysis of the COVID-19 Registry of the Spanish Society of Nephrology.
Material and methods: The Registry began operating on March 18th, 2020. It collects epidemiological variables, contagion and diagnosis data, signs and symptoms, treatments and outcomes. It is an online registry. Patients were diagnosed with SARS-CoV-2 infection based on the results of the PCR of the virus, carried out both in patients who had manifested compatible symptoms or had suspicious signs, as well as in those who had undergone screening after some contact acquainted with another patient.
Conflicts of interest The authors have no conflicts of interest to declare.
References
Chen, Liu, Liu, Xu, Xia et al., A pilot study of hydroxychloroquine in treatment of patients with common coronavirus disease-19 (COVID19), J Zhejiang Univ (Med Sci,
doi:10.3785/j.issn.1008-9292.2020.03.03Ferrey, Choi, Hanna, Chang, Tantisattamo et al., A case of novel coronavirus disease 19 in a chronic hemodialysis patient presenting with gastroenteritis and developing severe pulmonary disease, Am J Nephrol,
doi:10.1159/000507417Garg, Kim, Whitaker, 'halloran, Cummings et al., Hospitalization rates and characteristics of patients hospitalized with laboratory-confirmed coronavirus disease COVID-NET-2019, 14 States, MMWR Morb Mortal Wkly Rep,
doi:10.15585/mmwr.mm6915e3Gautret, Lagier, Parola, Hoang, Meddeb et al., Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label nonrandomized clinical trial, Int J Antimicrob Agents
Guan, Ni, Hu, Liang, Ou et al., Clinical characteristics of coronavirus disease 2019 in China, N Engl J Med,
doi:10.1056/NEJMoa2002032Henry, Lippi, Chronic kidney disease is associated with severe coronavirus disease 2019 (COVID-19) infection, Int Urol Nephrol,
doi:10.1007/s11255-020-02451-9Hoffmann, Kleine-Weber, Schroeder, Krüger, Herrler et al., SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor, Cell,
doi:10.3785/j.issn.1008-9292.2020.03.03Kuba, Imai, Rao, Gao, Guo et al., A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury, Nat Med,
doi:10.1016/j.cell.2020.02.052Liu, Huang, Xu, Yang, Qin et al., Anti-hypertensive Angiotensin II receptor blockers associated to mitigation of disease severity in elderly COVID-19 patients, medRxiv,
doi:10.1101/2020.03.20.20039586Liu, Zhao, Liu, Xu, Wong et al., T-cell immunity of SARS-CoV: implications for vaccine development against MERS-CoV, Antiviral Res
Paton, Lee, Xu, Ooi, Cheung et al., Chloroquine for influenza prevention: a randomized, double-blind, placebo controlled trial, Lancet Infect Dis
Vaziri, Pahl, Crum, Norris, Effect of uremia on structure and function of immune system, J Ren Nutr
Wang, Hu, Hu, Zhu, Liu et al., Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China, JAMA
Zhu, Xu, Ma, Yang, Guan et al., Successful recovery of COVID-19 pneumonia in a renal transplant recipient with long-term immunosuppression, Am J Transplant,
doi:10.1111/ajt.15869
