Analgesics
Antiandrogens
Azvudine
Bromhexine
Budesonide
Colchicine
Conv. Plasma
Curcumin
Famotidine
Favipiravir
Fluvoxamine
Hydroxychlor..
Ivermectin
Lifestyle
Melatonin
Metformin
Minerals
Molnupiravir
Monoclonals
Naso/orophar..
Nigella Sativa
Nitazoxanide
Paxlovid
Quercetin
Remdesivir
Thermotherapy
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c19early.org COVID-19 treatment researchSelect treatment..Select..
Melatonin Meta
Metformin Meta
Azvudine Meta
Bromhexine Meta Molnupiravir Meta
Budesonide Meta
Colchicine Meta
Conv. Plasma Meta Nigella Sativa Meta
Curcumin Meta Nitazoxanide Meta
Famotidine Meta Paxlovid Meta
Favipiravir Meta Quercetin Meta
Fluvoxamine Meta Remdesivir Meta
Hydroxychlor.. Meta Thermotherapy Meta
Ivermectin Meta

COVID-19 treatment cost effectiveness

April 2024
c19early.org
Cost per life saved from NNT in
studies to date
Melatonin
9
48%
  $8
Vitamin D
67
36%
  $11
Alkalinization
8
46%
  $11
Zinc
20
29%
  $16
Vitamin C
42
19%
  $17
Ivermectin
51
49%
  $25
Colchicine
42
29%
  $26
HCQ
250
25%
  $27
Aspirin
63
11%
  $33
Vitamin A
5
30%
  $45
Curcumin
8
63%
  $59
Famotidine
21
18%
  $94
Probiotics
8
61%
  $99
Quercetin
5
61%
  $127
Metformin
63
34%
  $144
Antiandrogens
32
37%
  $179
Nigella Sativa
5
57%
  $187
Budesonide
12
26%
  $574
Nitazoxanide
6
42%
  $680
Azvudine
13
34%
  $1,237
Fluvoxamine
9
43%
  $1,283
Favipiravir
38
12%
  $1,717
Tixagev../c..
10
42%
  $74,506
Molnupiravir
18
22%
  $148,470
Paxlovid
28
31%
  $157,070
Casirivimab/i..
9
31%
  $203,958
Bamlaniv../e..
12
56%
  $269,237
Sotrovimab
10
49%
  $352,800
Regdanvimab
6
74%
  $389,130
Bebtelovimab
4
60%
  $737,601
Remdesivir
59
4%
  $1,558,440
Conv. Plasma
45
-1%
N/A
Acetaminophen
14
-24%
N/A
Treatment cost times the median NNT (number needed to treat) from studies reporting mortality results with calculable NNT. The numbers on the right are the number of mortality results and the corresponding improvement from meta analysis. Costs are shown in $US and based on estimated costs for widespread distribution by governments. Results reflect conditions as used in trials to date, these depend on the population treated, treatment delay, and treatment regimen. For example, vitamin C results are dominated by very late treatment studies with high control mortality. Click the treatment name to see all studies, where the name of each study can be clicked on for the source paper. No treatment is 100% effective. Protocols typically combine multiple treatments which may be complementary and synergistic. Treatment efficacy may vary by variant, especially for monoclonal antibodies. Only medications with ≥3 results are shown. Cost per life saved may increase for variants with lower virulence. All treatments have potential side effects. All practical, effective, and safe means should be used based on risk/benefit analysis. Key: Benefit  Benefit without statistical significance  Harm  Number of studies
Estimated benefit
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Please send us corrections, updates, or comments. c19early involves the extraction of 100,000+ datapoints from thousands of papers. Community updates help ensure high accuracy. Treatments and other interventions are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. FLCCC and WCH provide treatment protocols.
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