HC Q study #63
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Pre-Exposure Prophylaxis study (treated before exposed to the virus)
Khurana et al., medRxiv, doi:10.1101/2020.07.21.20159301 (Preprint)
Prevalence and clinical correlates of COVID-19 outbreak among healthcare workers in a tertiary level hospital
Study of hospital health care workers showing HC Q prophylaxis reduces COVID-19 significantly, OR 0.30, p=0.02. 94 positive health care workers with a matched sample of 87 testing negative. Full course prophylaxis was important in this study which used a low dose of 400mg/week HC Q (800mg for week 1), so it may take longer to reach therapeutic levels. Actual benefit of HC Q may be larger because severity of symptoms are not considered here but HC Q may also reduce severity.
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